Pharmacogenetics of psychotropic drugs

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Psychotropic drugs

The interaction between the cognitive component (the perception of nociceptive, or painful stimuli) and the affective component of pain is reflected in the overlap between the actions of anti-nociceptive agents (analgesics) and mood-altering drugs (psychotropics) when treating pain patients. Anxiety, depression, fear and sleeplessness may all respond to psychotropic drugs, and this may result i...

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[Psychotropic drugs].

The interaction between the cognitive component (the perception of nociceptive, or painful stimuli) and the affective component of pain is reflected in the overlap between the actions of anti-nociceptive agents (analgesics) and mood-altering drugs (psychotropics) when treating pain patients. Anxiety, depression, fear and sleeplessness may all respond to psychotropic drugs, and this may result i...

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Psychotropic drugs.

Introduction Of the many patients with psychological illness or disorders in which emotional factors are important, a large proportion are given psychotropic drugs. Many improve because of this treatment and some despite it. The potent agents now available are liable to produce side-effects or toxic effects which have to be set against the potential benefits conferred by these drugs. If drug tr...

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Cases of Adverse Reaction to Psychotropic Drugs and Possible Association with Pharmacogenetics

Thousands of samples for pharmacogenetic tests have been analysed in our laboratory since its establishment. In this article we describe some of the most interesting cases of CYP poor metabolisers associated with adverse reactions to psychotropic drugs. Prevention of disease/illness, including Adverse Drug Reaction (ADR), is an aim of modern medicine. Scientific data supports the fact that eval...

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Pharmacogenetics of analgesic drugs

• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined. • Analgesics act in various ways on the peripheral and central pain pathways and are regarded as one of the most valuable but equally dangerous groups of medications. • While pharmacokinetic properties of drugs, metabolism in particular, ...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 2003

ISSN: 0022-3050

DOI: 10.1136/jnnp.74.12.1700-b